Publications

Fisher, M. J.; McMurray, L.; Lu, S.; Morse, C. L.; Liow, J.-S.; Zoghbi, S. S.; Kowalski, A.; Tye, G. L.; Innis, R. B.; Aigbirhio, F. I.; Pike, V. W. Front Cover: [Carboxyl-11C]Labelling of Four High-Affinity cPLA2α Inhibitors and Their Evaluation as Radioligands in Mice by Positron Emission Tomography (ChemMedChem 2/2018). ChemMedChem 2018, 13 (2), 127.

• Fisher, M. J.; McMurray, L.; Lu, S.; Morse, C. L.; Liow, J.-S.; Zoghbi, S. S.; Kowalski, A.; Tye, G. L.; Innis, R. B.; Aigbirhio, F. I.; Pike, V. W. [Carboxyl-11C]Labelling of Four High-Affinity cPLA2α Inhibitors and Their Evaluation as Radioligands in Mice by Positron Emission Tomography. ChemMedChem 2018, 13 (2), 138–146.
• Jensen-Kondering, U.; Manavaki, R.; Ejaz, S.; Sawiak, S. J.; Carpenter, T. A.; Fryer, T. D.; Aigbirhio, F. I.; Williamson, D. J.; Baron, J.-C. Brain Hypoxia Mapping in Acute Stroke: Back-to-Back T2’ MR versus18F-Fluoromisonidazole PET in Rodents. Int. J. Stroke 2017, 12 (7), 752–760
• Ge, H.; Riss, P. J.; Mirabello, V.; Calatayud, D. G.; Flower, S. E.; Arrowsmith, R. L.; Fryer, T. D.; Hong, Y.; Sawiak, S.; Jacobs, R. M. J.; Botchway, S. W.; Tyrrell, R. M.; James, T. D.; Fossey, J. S.; Dilworth, J. R.; Aigbirhio, F. I.; Pascu, S. I. Behavior of Supramolecular Assemblies of Radiometal-Filled and Fluorescent Carbon Nanocapsules In Vitro and In Vivo. Chem 2017, 3 (3), 437–460.
• Hall, B.; Mak, E.; Cervenka, S.; Aigbirhio, F. I.; Rowe, J. B.; O’Brien, J. T. In Vivo Tau PET Imaging in Dementia: Pathophysiology, Radiotracer Quantification, and a Systematic Review of Clinical Findings. Ageing Res. Rev. 2017, 36, 50–63.
• Fryer, T. D.; Jensen-Kondering, U.; Williamson, D. J.; Sawiak, S. J.; Aigbirhio, F. I.; Hong, Y. T.; Ejaz, S.; Jensen-Kondering, U.; Sitnikov, S.; Baron, J.-C.; Jensen-Kondering, U.; Baron, J.-C. Effects of Hyperoxia on 18F-Fluoro-Misonidazole Brain Uptake and Tissue Oxygen Tension Following Middle Cerebral Artery Occlusion in Rodents: Pilot Studies. PLoS One 2017, 12 (11), e0187087.
• Joshi, F. R.; Manavaki, R.; Fryer, T. D.; Figg, N. L.; Sluimer, J. C.; Aigbirhio, F. I.; Davenport, A. P.; Kirkpatrick, P. J.; Warburton, E. A.; Rudd, J. H. F. Vascular Imaging With (18)F-Fluorodeoxyglucose Positron Emission Tomography Is Influenced by Hypoxia. J. Am. Coll. Cardiol. 2017, 69 (14), 1873–1874.
• Passamonti, L.; Vazquez, R. P.; Hong, Y. T.; Borchert, R. J.; Sami, S.; Cope, T. E.; Jones, P. S.; Fryer, T. D.; Aigbirhio, F. I.; Rowe, J. B.; Passamonti, L.; Hong, Y. T.; Williamson, D.; Fryer, T. D.; Aigbirhio, F. I.; Allinson, K. S. J.; Bevan-Jones, W. R.; Arnold, R.; Surendranathan, A.; Mak, E.; Su, L.; O’Brien, J. T. 18F-AV-1451 Positron Emission Tomography in Alzheimer’s Disease and Progressive Supranuclear Palsy. Brain 2017, 140 (3), 781–791.
• Bevan-Jones, W. R.; Surendranathan, A.; Arnold, R.; Mak, E.; Su, L.; O’Brien, J. T.; Passamonti, L.; Vazquez, R. P.; Rowe, J. B.; Coles, J. P.; Fryer, T. D.; Hong, Y. T.; Williams, G.; Aigbirhio, F. Neuroimaging of Inflammation in Memory and Related Other Disorders (NIMROD) Study Protocol: A Deep Phenotyping Cohort Study of the Role of Brain Inflammation in Dementia, Depression and Other Neurological Illnesses. BMJ Open 2017, 7 (1), e013187.
• Bevan-Jones, W. R.; Cope, T. E.; Jones, P. S.; Passamonti, L.; Hong, Y. T.; Fryer, T. D.; Arnold, R.; Allinson, K. S. J.; Coles, J. P.; Aigbirhio, F. I.; Patterson, K.; O’Brien, J. T.; Rowe, J. B. [18F]AV-1451 Binding in Vivo Mirrors the Expected Distribution of TDP-43 Pathology in the Semantic Variant of Primary Progressive Aphasia. J. Neurol. Neurosurg. Psychiatry 2017, jnnp-2017-316402.
• Fisher, E.; Zhao, Y.; Richardson, R.; Janik, M.; Buell, A. K.; Aigbirhio, F. I.; Tóth, G. Detection and Characterization of Small Molecule Interactions with Fibrillar Protein Aggregates Using Microscale Thermophoresis. ACS Chem. Neurosci. 2017, 8 (9), 2088–2095.
• Ejaz, S.; Emmrich, J. V; Sitnikov, S. L.; Hong, Y. T.; Sawiak, S. J.; Fryer, T. D.; Aigbirhio, F. I.; Williamson, D. J.; Baron, J.-C. Normobaric Hyperoxia Markedly Reduces Brain Damage and Sensorimotor Deficits Following Brief Focal Ischaemia. Brain 2016, 139 (Pt 3), 751–764.
• Bevan Jones, W. R.; Cope, T. E.; Passamonti, L.; Fryer, T. D.; Hong, Y. T.; Aigbirhio, F.; Kril, J. J.; Forrest, S. L.; Allinson, K.; Coles, J. P.; Simon Jones, P.; Spillantini, M. G.; Hodges, J. R.; O’Brien, J. T.; Rowe, J. B. [18F]AV-1451 PET in Behavioral Variant Frontotemporal Dementia due to MAPT Mutation. Ann. Clin. Transl. Neurol. 2016, 3 (12), 940–947.
• Betts, H. M.; Milicevic Sephton, S.; Tong, C.; Awais, R. O.; Hill, P. J.; Perkins, A. C.; Aigbirhio, F. I. Synthesis, in Vitro Evaluation, and Radiolabeling of Fluorinated Puromycin Analogues: Potential Candidates for PET Imaging of Protein Synthesis. J. Med. Chem. 2016, 59 (20), 9422–9430.
• Milicevic Sephton, S.; Aigbirhio, F. I. Radiosynthesis of Carbon-11 Labeled Puromycin as a Potential PET Candidate for Imaging Protein Synthesis in Vivo. ACS Med. Chem. Lett. 2016, 7 (6), 647–651.
• Aigbirhio, F. I.; Allwein, S.; Anwar, A.; Atzrodt, J.; Audisio, D.; Badman, G.; Bakale, R.; Berthon, F.; Bragg, R.; Brindle, K. M.; Bushby, N.; Campos, S.; Cant, A. A.; Chan, M. Y. T.; Colbon, P.; Cornelissen, B.; Czarny, B.; Derdau, V.; Dive, V.; Dunscombe, M.; Eggleston, I.; Ellis-Sawyer, K.; Elmore, C. S.; Engstrom, P.; Ericsson, C.; Fairlamb, I. J. S.; Georgin, D.; Godfrey, S. P.; He, L.; Hickey, M. J.; Huscroft, I. T.; Kerr, W. J.; Lashford, A.; Lenz, E.; Lewinton, S.; L’Hermite, M. M.; Lindeloef, A.; Little, G.; Lockley, W. J. S.; Loreau, O.; Maddocks, S.; Marguerit, M.; Mirabello, V.; Mudd, R. J.; Nilsson, G. N.; Owens, P. K.; Pascu, S. I.; Patriarche, G.; Pimlott, S. L.; Pinault, M.; Plastow, G.; Racys, D. T.; Reif, J.; Rossi, J.; Ruan, J.; Sarpaki, S.; Sephton, S. M.; Simonsson, R.; Speed, D. J.; Sumal, K.; Sutherland, A.; Taran, F.; Thuleau, A.; Wang, Y.; Waring, M.; Watters, W. H.; Wu, J.; Xiao, J. Abstracts of the 24th International Isotope Society (UK Group) Symposium: Synthesis and Applications of Labelled Compounds 2015. J. Label. Compd. Radiopharm. 2016, 59 (4), 175–186.
•   Mendichovszky, I. A.; Manavaki, R.; Gilbert, F. J.; Powlson, A. S.; Gurnell, M.; Aigbirhio, F. I.; Cheow, H.; Buscombe, J. R. Targeted Molecular Imaging in Adrenal Disease-An Emerging Role for Metomidate PET-CT. Diagnostics (Basel, Switzerland) 2016, 6 (4).
• Belton, M.; Brilha, S.; Dembek, M.; Green, J.; Moores, R.; Elkington, P. T.; Friedland, J. S.; Manavaki, R.; Mauri, F.; Nijran, K.; Patel, N. H.; Al-Nahhas, A.; Hong, Y. T.; Aigbirhio, F.; Fryer, T. D.; Tezera, L.; Elkington, P. T. Hypoxia and Tissue Destruction in Pulmonary TB. Thorax 2016, 71 (12), 1145–1153.
• Veenith, T. V; Carter, E. L.; Newcombe, V. F. J.; Outtrim, J.; Menon, D. K.; Coles, J. P.; Geeraerts, T.; Grossac, J.; Gee, G. S.; Lupson, V.; Smith, R.; Aigbirhio, F. I.; Fryer, T. D.; Hong, Y. T. Pathophysiologic Mechanisms of Cerebral Ischemia and Diffusion Hypoxia in Traumatic Brain Injury. JAMA Neurol. 2016, 73 (5), 542–550.
•   Annus, T.; Wilson, L. R.; Hong, Y. T.; Fryer, T. D.; Smith, R.; Boros, I.; Aigbirhio, F. I.; Acosta-Cabronero, J.; Cardenas-Blanco, A.; Nestor, P. J.; Coles, J. P.; Menon, D. K.; Zaman, S. H.; Holland, A. J. The Pattern of Amyloid Accumulation in the Brains of Adults with Down Syndrome. Alzheimers. Dement. 2016, 12 (5), 538–545.
• Koulouri, O.; Kandasamy, N.; Hoole, A. C.; Gillett, D.; Heard, S.; Powlson, A. S.; O’Donovan, D. G.; Annamalai, A. K.; Simpson, H. L.; Akker, S. A.; Aylwin, S. J. B.; Brooke, A.; Buch, H.; Levy, M. J.; Martin, N.; Morris, D.; Parkinson, C.; Tysome, J. R.; Santarius, T.; Donnelly, N.; Buscombe, J.; Boros, I.; Smith, R.; Aigbirhio, F.; Antoun, N. M.; Burnet, N. G.; Cheow, H.; Mannion, R. J.; Pickard, J. D.; Gurnell, M. Successful Treatment of Residual Pituitary Adenoma in Persistent Acromegaly Following Localisation by 11C-Methionine PET Co-Registered with MRI. Eur. J. Endocrinol. 2016, 175 (5), 485–498.
• Farid, K.; Hong, Y. T.; Aigbirhio, F. I.; Fryer, T. D.; Menon, D. K.; Warburton, E. A.; Baron, J.-C. Early-Phase 11C-PiB PET in Amyloid Angiopathy-Related Symptomatic Cerebral Hemorrhage: Potential Diagnostic Value?. PLoS One 2015, 10 (10), e0139926/1-e0139926/11.
• Kiss, R.; Aigbirhio, F.; Toth, G. Seeking Alpha-Synuclein Ligands by Structure-Based in Silico Screening. In Abstracts of Papers, 250th ACS National Meeting & Exposition, Boston, MA, United States, August 16-20, 2015; American Chemical Society, 2015; p COMP-263.
•   Caprioli, D.; Jupp, B.; Hong, Y. T.; Sawiak, S. J.; Ferrari, V.; Wharton, L.; Williamson, D. J.; McNabb, C.; Berry, D.; Aigbirhio, F. I.; Robbins, T. W.; Fryer, T. D.; Dalley, J. W. Dissociable Rate-Dependent Effects of Oral Methylphenidate on Impulsivity and D2/3 Receptor Availability in the Striatum. J. Neurosci. 2015, 35 (9), 3747–3755.
•   Li, L.; Shao, X.; Cole, E. L.; Ohnmacht, S. A.; Ferrari, V.; Hong, Y. T.; Williamson, D. J.; Fryer, T. D.; Quesada, C. A.; Sherman, P.; Riss, P. J.; Scott, P. J. H.; Aigbirhio, F. I. Synthesis and Initial in Vivo Studies with [11C]SB-216763: The First Radiolabeled Brain Penetrative Inhibitor of GSK-3. ACS Med. Chem. Lett. 2015, 6 (5), 548–552.
•   Charidimou, A.; Hong, Y. T.; Jager, H. R.; Fox, Z.; Aigbirhio, F. I.; Fryer, T. D.; Menon, D. K.; Warburton, E. A.; Werring, D. J.; Baron, J.-C. White Matter Perivascular Spaces on Magnetic Resonance Imaging: Marker of Cerebrovascular Amyloid Burden? Stroke 2015, 46 (6), 1707–1709.